Screening small molecule fragments has made it possible to identify pharmacological leads against otherwise hard to target hotspots on biomolecules, such as allosteric sites, rendering this approach a valuable alternative method of drug discovery
The report features an extensive study of the current market landscape, offering an informed opinion on the likely adoption of this approach over the next decade. It features an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this domain. In addition to other elements, the study includes:
· A detailed review of the overall landscape of fragment-based drug discovery library and service providers.
· Elaborate profiles of the companies providing libraries and services for fragment-based drug discovery (shortlisted on the basis of the service portfolio and number of fragment screening techniques offered).
· An analysis of the partnerships that have been established in the recent past.
· A detailed analysis on acquisition targets.
· An insightful competitiveness analysis of fragment-based drug discovery library and service providers.
· An analysis highlighting the cost saving potential associated with the use of fragment-based drug discovery approach.
Chapter 2 is an executive summary of the insights captured in our research. It offers a high-level view on the current state of the market for fragment-based drug discovery and its likely evolution in the short-mid-term and long term.
Chapter 3 provides an introduction to the process of drug discovery and development. In addition, the chapter focuses on the concept of fragment-based drug discovery, highlighting its key advantages and drawbacks. It also features a brief discussion on the opportunities and the likely future trends in this field.
Chapter 4 provides a detailed overview of the current market landscape of fragment-based drug discovery, including information on library and service providers, type of product (library and technology), type of service offered (fragment screening and fragment optimization), type of technique used (X-ray crystallography, nuclear magnetic resonance, surface plasmon resonance, and other screening techniques), other services offered (target identification / validation, hit identification, hit-to-lead / lead generation and lead optimization) and end user (industry players and non-industry players).
Chapter 5 includes detailed profiles of the companies providing library and services for fragment-based drug discovery (shortlisted on the basis of the service portfolio and number of fragment screening techniques offered). Each profile features a brief overview of the company, its financial information (if available), fragment-based library and service portfolio, information on other drug discovery services, recent developments and an informed future outlook.
Chapter 6 features an elaborate analysis of the partnerships that have been inked among various stakeholders in this domain, during 2015-2020. It includes a brief description of partnership models (such as research and development agreements, mergers and acquisitions, product development and commercialization agreements, distribution and supply agreements, service alliances, and commercialization agreements) adopted by the stakeholders.
Chapter 7 provides a detailed acquisition target analysis, taking into consideration the historical trend of the activity of the companies that have acquired other firms since 2015, and offering a means for other industry stakeholders to identify potential acquisition targets.
Chapter 8 provides an insightful competitiveness analysis of fragment-based drug discovery library and service providers, featuring a two-dimensional scatter plot representation. It highlights the key players in this domain, taking into consideration the supplier power (based on the year of establishment of service provider) and key specifications, such as number of fragment libraries and number of screening techniques.
Chapter 9 provides an analysis highlighting the cost saving potential associated with the use of fragment-based drug discovery approach.
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