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Use of LDN for autoimmunity and chronic pain

Low dose Naltrexone (LDN) for autoimmunity and chronic pain

Low Dose Naltrexone (LDN) is right now being investigated in patients having different types of chronic pain such as fibromyalgia, migraines, neuropathy as well as several other chronic pain conditions, many kinds of cancers, and autoimmune disorders. While the research is advancing in the U.S., LDN is being taken widely for various pain-related diseases and autoimmune disorders.

Studies reveal that Low Dose Naltrexone is Safe.

Modern studies prove that LDN is a safe, yet efficient treatment option for chronic pain and autoimmunity. It is understood that Low Dose Naltrexone acts in the brain by decreasing pro-inflammatory substances called cytokines that are recognized to inflame and stimulate various tissues to induce pain. By downregulating this process in the nervous system, low-dose naltrexone decreases pain, increases fatigue, and mood along with physical function.

Low Dose Naltrexone in comparison to high dosage Naltrexone is still being considered as investigational by the FDA. LDN is nonproprietary and is cost-friendly. LDN has to be compounded at a compounding pharmacy as it is just available in the 50 mg dose at regular pharmacies. While the standard dose of Naltrexone is being used for several years to tackle several forms of dependence, no addiction linked with Naltrexone use has been observed. The estimated cost of compounded LDN is about $50/month.

How do you use it?

The beginner's dose is 0.5 to 1.0 mg taken at bedtime which is slowly increased up to the target dose of 4.0 – 4.5 mg. You will be given 1.0 mg at night before sleeping and every 30 days your dose will be increased by 1.0 mg till you observe improvement up to the highest dose of 4mg.

Side effects of LDN are rarely observed. People seldomly talk of having vivid dreams during the first two weeks of treatment. Extremely uncommon side effects of LDN involve anxiety, fatigue, and dizziness. Side effects are considerably common at the greater doses (10 times greater than that of LDN dose) given to treat dependence and are uncommonly witnessed with regular Low Dose Naltrexone dosages. People who are taking immunosuppressive drugs or getting organ transplants should avoid the use of LDN.


Only a Compounding Pharmacy can offer you LDN

To explore more about low-dose naltrexone and the conditions it treats, or if you have any queries regarding LDN, or if you want to obtain it with your doctor's prescription, you can contact Harbor Compounding Pharmacy to receive the assistance you're looking for.


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