Florfenicol is the most sensitive species among amidoalcohol antibiotics, besides chloramphenicol and thiamphenicol. Chloramphenicol has been banned, and thiamphenicol has been tepid for many years due to sensitivity and food safety issues, and it will be eliminated sooner or later.
Florfenicol is a special antibacterial drug for animals. Under the background of the reality that many veterinary drug products are shared by humans and animals, it is relatively rare to have such a unique broad-spectrum antibacterial drug. Moreover, the withdrawal period of florfenicol for oral administration to poultry is only 5 days. For the poultry industry with a relatively short breeding cycle, there are many opportunities to use it in the treatment of some bacterial and mycoplasma respiratory diseases.
However, the clinical therapeutic value of florfenicol in poultry and veterinary medicine has not been fully utilized and demonstrated.
The main reason for the current situation is the vast number of grassroots veterinary workers and Florfenicol users. Everyone will not use Florfenicol! So, what does it mean to use Florfenicol? One is that you will choose targeted products according to different animals; the other is that you will issue targeted prescriptions based on different diseases. For pig health care, it is best to use Florfenicol premix; for pig emergency treatment, it is best to use Florfenicol injection!
Choice > The technical characteristics of the treatment preparations are different, and the best chances for the application are
different .
Premix and 20% florfenicol powder and other products in different dosage forms, in the development of so many dosage forms of florfenicol products, according to the research and development strength of each manufacturer, everyone will make products with different preparation technical characteristics . Therefore, as a Florfenicol user, you must have the ability to identify and select the most suitable product.
Florfenicol products cannot be used by anyone who sells them. Different dosage forms of Florfenicol products are suitable for poultry. For example, because the release of florfenicol premix is relatively slow, it will be excreted before it is fully absorbed by poultry orally, which is basically useless! Therefore, if it is used for chickens, the use of florfenicol soluble powder is the best choice; and if it is used for the treatment of waterfowl diseases, the use of florfenicol injection is the best choice.
Moreover, the same florfenicol soluble powder product is called florfenicol soluble powder just from the packaging. In fact, different preparation techniques will also make the clinical performance of the product different. For example, there are two chiral carbon atoms in the molecular structure of Florfenicol, so there are two configurations of Florfenicol: L-Florfenicol and D-Florfenicol. Although the raw materials of florfenicol on the market are the same, they are all levorotary (threo-style) florfenicol. However, due to the different preparation techniques, the stability of florfenicol products from different manufacturers is also different.
Because of the chiral characteristics of Florfenicol, the stability of its dominant configuration is conditional. For example, the stability of acid and alkali, florfenicol is the most stable when the pH is 4.5-7.5; and florfenicol will degrade in strong acid and strong alkali environment. Among some excipients, florfenicol is the most stable in the form of dextrorotary; so although you use levoflorfenicol for production, it will undergo crystal transformation during product storage—becoming less active Dexflorfenicol.
This is the first aspect we talk about using florfenicol well, so many florfenicol preparations: powder, soluble powder, injection, premix, etc., so many florfenicol preparation technologies: super Molecular inclusion technology, cyclodextrin coating technology, solid dispersion technology, chemical solubilization technology, which drug dosage form, which preparation technical characteristics of florfenicol products are most suitable for the disease of the animal you are going to treat ?
Can a good product be put into a beneficial formula to have a good effect?
The diseases that occur in the current poultry farming are not single simple infection, most of them are mixed infection. What's more, each infection will cause various pathological changes to the body, such as the most common symptoms or pathological changes such as runny nose, mucus, dyspnea, fever, cough, snoring, bleeding, and edema. Therefore, treatment requires a prescription, and good products can only have good curative effect if they are placed in a good prescription.
In addition, there are drug resistance issues, antibacterial spectrum issues, synergistic issues, etc., all of which involve overall disease identification, combination of causes and symptoms, combination compatibility, and prescription drugs, so that comprehensive, rapid and economical treatment can be achieved. The disease can be effectively controlled, and the health and normal production of the flock can be effectively restored. Therefore, for acute systemic infectious diseases, the use of "florfenicol soluble powder + doxycycline hydrochloride soluble powder + acetaminophen injection" is more thorough than using florfenicol alone.
For the treatment of livestock and poultry digestive tract diseases, using the above prescription is not the best choice. At this time, the prescription of "florfenicol soluble powder + colistin sulfate soluble powder + berberine" should be used, which is effective and economical for the treatment of adenoid gastritis and enteritis.
If it is used for the treatment of serositis caused by a large number of waterfowl deaths, it is necessary to use "florfenicol injection + acetaminophen injection", and the therapeutic effect of injection can stop the death. Therefore, only by selecting suitable and characteristic products and putting such products into a targeted veterinary treatment prescription can we use florfenicol to cure diseases and maximize its drug value.
https://www.arshinepharma.com/?info/florfenicol-be-used.html
How should florfenicol be used to maximize its drug effect?
Florfenicol is the most sensitive species among amidoalcohol antibiotics, besides chloramphenicol and thiamphenicol. Chloramphenicol has been banned, and thiamphenicol has been tepid for many years due to sensitivity and food safety issues, and it will be eliminated sooner or later.
Florfenicol is a special antibacterial drug for animals. Under the background of the reality that many veterinary drug products are shared by humans and animals, it is relatively rare to have such a unique broad-spectrum antibacterial drug. Moreover, the withdrawal period of florfenicol for oral administration to poultry is only 5 days. For the poultry industry with a relatively short breeding cycle, there are many opportunities to use it in the treatment of some bacterial and mycoplasma respiratory diseases.
However, the clinical therapeutic value of florfenicol in poultry and veterinary medicine has not been fully utilized and demonstrated.
The main reason for the current situation is the vast number of grassroots veterinary workers and Florfenicol users. Everyone will not use Florfenicol! So, what does it mean to use Florfenicol? One is that you will choose targeted products according to different animals; the other is that you will issue targeted prescriptions based on different diseases. For pig health care, it is best to use Florfenicol premix; for pig emergency treatment, it is best to use Florfenicol injection!
Choice > The technical characteristics of the treatment preparations are different, and the best chances for the application are
different .
Premix and 20% florfenicol powder and other products in different dosage forms, in the development of so many dosage forms of florfenicol products, according to the research and development strength of each manufacturer, everyone will make products with different preparation technical characteristics . Therefore, as a Florfenicol user, you must have the ability to identify and select the most suitable product.
Florfenicol products cannot be used by anyone who sells them. Different dosage forms of Florfenicol products are suitable for poultry. For example, because the release of florfenicol premix is relatively slow, it will be excreted before it is fully absorbed by poultry orally, which is basically useless! Therefore, if it is used for chickens, the use of florfenicol soluble powder is the best choice; and if it is used for the treatment of waterfowl diseases, the use of florfenicol injection is the best choice.
Moreover, the same florfenicol soluble powder product is called florfenicol soluble powder just from the packaging. In fact, different preparation techniques will also make the clinical performance of the product different. For example, there are two chiral carbon atoms in the molecular structure of Florfenicol, so there are two configurations of Florfenicol: L-Florfenicol and D-Florfenicol. Although the raw materials of florfenicol on the market are the same, they are all levorotary (threo-style) florfenicol. However, due to the different preparation techniques, the stability of florfenicol products from different manufacturers is also different.
Because of the chiral characteristics of Florfenicol, the stability of its dominant configuration is conditional. For example, the stability of acid and alkali, florfenicol is the most stable when the pH is 4.5-7.5; and florfenicol will degrade in strong acid and strong alkali environment. Among some excipients, florfenicol is the most stable in the form of dextrorotary; so although you use levoflorfenicol for production, it will undergo crystal transformation during product storage—becoming less active Dexflorfenicol.
This is the first aspect we talk about using florfenicol well, so many florfenicol preparations: powder, soluble powder, injection, premix, etc., so many florfenicol preparation technologies: super Molecular inclusion technology, cyclodextrin coating technology, solid dispersion technology, chemical solubilization technology, which drug dosage form, which preparation technical characteristics of florfenicol products are most suitable for the disease of the animal you are going to treat ?
Can a good product be put into a beneficial formula to have a good effect?
The diseases that occur in the current poultry farming are not single simple infection, most of them are mixed infection. What's more, each infection will cause various pathological changes to the body, such as the most common symptoms or pathological changes such as runny nose, mucus, dyspnea, fever, cough, snoring, bleeding, and edema. Therefore, treatment requires a prescription, and good products can only have good curative effect if they are placed in a good prescription.
In addition, there are drug resistance issues, antibacterial spectrum issues, synergistic issues, etc., all of which involve overall disease identification, combination of causes and symptoms, combination compatibility, and prescription drugs, so that comprehensive, rapid and economical treatment can be achieved. The disease can be effectively controlled, and the health and normal production of the flock can be effectively restored. Therefore, for acute systemic infectious diseases, the use of "florfenicol soluble powder + doxycycline hydrochloride soluble powder + acetaminophen injection" is more thorough than using florfenicol alone.
For the treatment of livestock and poultry digestive tract diseases, using the above prescription is not the best choice. At this time, the prescription of "florfenicol soluble powder + colistin sulfate soluble powder + berberine" should be used, which is effective and economical for the treatment of adenoid gastritis and enteritis.
If it is used for the treatment of serositis caused by a large number of waterfowl deaths, it is necessary to use "florfenicol injection + acetaminophen injection", and the therapeutic effect of injection can stop the death. Therefore, only by selecting suitable and characteristic products and putting such products into a targeted veterinary treatment prescription can we use florfenicol to cure diseases and maximize its drug value.
https://www.arshinepharma.com/?info/florfenicol-be-used.html
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